Systems Biology for Metabolic Disease

Mapping theregulatory logicof diabetes genomics.

BDB Genomics builds computational pipelines for chromatin accessibility, regulatory modeling, and translational analysis centered on type 2 diabetes.

ATAC-seq

Chromatin accessibility workflows

RNA-seq

Regulatory signal integration

T2D

Disease-focused systems analysis

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Mission

Decode how regulatory programs shape metabolic disease and turn multi-omic data into usable biological insight.

Focus

Interpretable epigenomics for type 2 diabetes

Research Focus

Built around regulatory mechanisms, not generic analytics.

The lab emphasizes chromatin accessibility, integrative functional genomics, and computational workflows that stay interpretable across public and in-house datasets.

Regulatory Genomics

Pinpointing variants, cis-regulatory elements, and signal flow that shape type 2 diabetes phenotypes.

Epigenomic Integration

Combining chromatin accessibility, transcriptomic, and functional readouts into interpretable models.

Translational Datasets

Building robust pipelines that translate public and in-house data into biologically useful hypotheses.

Software

R packages that extend the research workflow.

BDB Genomics packages are positioned as practical interfaces for large-scale epigenomic and evolutionary analysis in reproducible R workflows.

AlphaGenomeR

Genome-scale tooling for epigenomic analysis, signal extraction, and regulatory interpretation.

R

Evo2R

Interfaces for evolutionary genomics workflows that connect sequence context with functional insight.

R
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Contact BDB Genomics

For collaborations, computational biology discussions, or package-related questions, reach out directly.

2032ushimanshu@gmail.com